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Genetic Mechanisms (IFWH0011)

Key information

Faculty
Faculty of Population Health Sciences
Teaching department
Ïã¸ÛÁùºÏ²Ê Elizabeth Garrett Anderson Institute for Women's Health
Credit value
15
Restrictions
The Genetic Mechanisms module requires a background in a relevant science-based discipline or a degree in medicine or nursing. The module is compulsory for student on the MSc Reproductive Genetics & Fetal Medicine. Preference will be given to Institute for Women's Health students for whom this module is compulsory and to Institute for Women's Health students for whom this is a recommended option.
Timetable

Alternative credit options

There are no alternative credit options available for this module.

Description

This module covers aspects of genetic mechanisms including non-coding RNA, X-inactivation, imprinting in physiology and cancer, epigenetics in inheritance and development, DNA repair mechanisms, cellular senescence, mitochondrial genetics, DNA origami, clinical genetics and diagnostics, antisense oligonucleotides, gene therapy.

After taking this module you should be able to demonstrate knowledge of:

  • genetic mechanisms including DNA replication and repair, the control of gene expression, senescence and apoptosis
  • how disruption of these mechanisms can lead to the genesis of chromosomal abnormalities, inherited disorders and cancer
  • how gene therapy and antisense oligonucleotides may be applied to treat some of these abnormalities
  • the academic and practical aspects involved in the grant application process

You should also have developed critical feedback skills through marking peer assessment.

The module is made up of lectures, tutorials, small group work and student seminar sessions.

Introductory Reading:
Strachan T and Read A (2011) Human Molecular Genetics 4th edition

Module deliveries for 2024/25 academic year

Intended teaching term: Term 1 ÌýÌýÌý Postgraduate (FHEQ Level 7)

Teaching and assessment

Mode of study
In person
Methods of assessment
100% Coursework
Mark scheme
Numeric Marks

Other information

Number of students on module in previous year
6
Module leader
Professor Simon Waddington
Who to contact for more information
ifwhadminteam@ucl.ac.uk

Last updated

This module description was last updated on 8th April 2024.

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