Description
This module helps you to understand the mechanisms of different cancer therapies, and how these relate to the underlying cancer biology. You will begin the module with workshops to develop your understanding of evidence based medicine and your skills for critical evaluation of clinical trials. You will then learn about the mechanisms and application of standard therapies (such as chemotherapy, radiotherapy and surgery), and of targeted therapies representing personalised cancer medicine, and the evidence supporting these. You will review the hallmarks of cancer, as defined by Hanahan and Weinberg, and will investigate how different therapies have been designed to target these hallmark features of cancer cells.
This module will consist of a mixture of lectures, interactive tutorials, discussion workshops and self-directed learning. You will also attend research-in-progress seminars from PhD students and postdoctoral researchers. Topics in this module include:
- Evidence Based Medicine
- Non-Targeted Cancer Therapies
- Therapies Targeting:– Sustained Proliferative Signalling
- Therapies Targeting:– Evasion of Growth Suppression
- Therapies Targeting:– Resistance to Cell Death
- Therapies Targeting:– Defective DNA Repair
- Therapies Targeting:– the Deregulation of Cellular Energetics
- Therapies Targeting:– the Induction of Angiogenesis
- Therapies Targeting:– the Enabling of Replicative Immortality
- Therapies Targeting:– the Activation of Invasion and Metastasis
Module deliveries for 2024/25 academic year
Last updated
This module description was last updated on 19th August 2024.
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